# CVE-2022-1521: 3.2.4 IMPROPER ACCESS CONTROL CWE-284

> Attackers can inject, replay, modify, or intercept sensitive data on Illumina sequencing instruments due to missing default authentication and authorization controls.

- **Severity:** Critical 9.1 (`CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:N`)
- **Exploited in the wild:** Not known
- **Login needed:** Not needed
- **Attackable:** Over the internet
- **Victim action needed:** Not needed
- **Fix available:** No
- **Published:** 24 Jun 2022
- **Updated:** 16 Apr 2025
- **Also known as:** GHSA-hgpf-hf44-725p

## What is CVE-2022-1521?

CVE-2022-1521 is a critical missing authorization vulnerability in Illumina MiSeq Dx, published on 24 Jun 2022. An attacker can exploit it over the internet without logging in, with no action from the victim.

### Official description

LRM does not implement authentication or authorization by default. A malicious actor can inject, replay, modify, and/or intercept sensitive data.

Weakness: CWE-862 (Missing Authorization), CWE-306 (Missing Authentication for Critical Functionality), CWE-284 (Improper Access Control)

## Which versions are affected by CVE-2022-1521?

It affects 1 product.


Products: Illumina Local Run Manager.

## How do I fix CVE-2022-1521?

No fix has been published for CVE-2022-1521 yet. Limit exposure of the affected software until one is available.

## Is CVE-2022-1521 being exploited?

There is no known exploitation of CVE-2022-1521 in the wild and no public exploit code.

## Other vulnerabilities in Illumina MiSeq Dx

- [CVE-2022-1517](https://insights.sbomify.com/CVE-2022-1517/): 3.2.1 EXECUTION WITH UNNECESSARY PRIVILEGES CWE-250 (critical 10.0)
- [CVE-2022-1518](https://insights.sbomify.com/CVE-2022-1518/): 3.2.2 IMPROPER LIMITATION OF A PATHNAME TO A RESTRICTED DIRECTORY ('PATH TRAVERSAL') CWE-22 (critical 10.0)
- [CVE-2022-1519](https://insights.sbomify.com/CVE-2022-1519/): File upload in MiSeq Dx (critical 10.0)
- [CVE-2022-1524](https://insights.sbomify.com/CVE-2022-1524/): 3.2.5 CLEARTEXT TRANSMISSION OF SENSITIVE INFORMATION CWE-319 (high 7.4)

## Fix prompt for AI coding agents

```text
Check this codebase for CVE-2022-1521 and fix it if it is affected.

What it is: CVE-2022-1521 is a critical missing authorization vulnerability in Illumina MiSeq Dx, published on 24 Jun 2022. An attacker can exploit it over the internet without logging in, with no action from the victim.
Exploitation: There is no known exploitation of CVE-2022-1521 in the wild and no public exploit code.

Affected product: Illumina MiSeq Dx. No package-level version data is available, so check the vendor advisory linked from the reference page.

Task:
1. Search the dependency manifests and lockfiles (for example package.json, package-lock.json, requirements.txt, poetry.lock, uv.lock, pom.xml, build.gradle, go.mod, Cargo.lock, Gemfile.lock) and any Dockerfiles for the affected packages, including transitive dependencies.
2. If an affected version is in use, upgrade it to the fixed version for its release line with the project's package manager, so the lockfile is regenerated. Prefer the smallest upgrade that fixes it.
3. If there is no fix, or the upgrade would break the build, do not guess: explain the risk and the safest workaround instead.
4. Run the tests and summarise what changed and why.
5. If nothing in the project is affected, say so and change nothing.

Reference: https://insights.sbomify.com/CVE-2022-1521/ (Markdown: https://insights.sbomify.com/CVE-2022-1521/index.md)
```

## Sources

- CVE record: https://www.cve.org/CVERecord?id=CVE-2022-1521
- NVD: https://nvd.nist.gov/vuln/detail/CVE-2022-1521
- OSV: https://osv.dev/vulnerability/CVE-2022-1521

---
From sbomify Insights: https://insights.sbomify.com/CVE-2022-1521/
Summaries are generated and may contain mistakes; the official description above is the record.