{"answers":{"affected":"3 open source packages ship an affected version, including biopython.","exploited":"There is no known exploitation of CVE-2025-68463 in the wild and no public exploit code.","fix":"Upgrade biopython to 1.87 or later.","what":"CVE-2025-68463 is a medium-severity vulnerability in Biopython, published on 18 Dec 2025. Any signed-in user can exploit it over the network, with no action from the victim."},"fix_prompt":"Check this codebase for CVE-2025-68463 and fix it if it is affected.\n\nWhat it is: CVE-2025-68463 is a medium-severity vulnerability in Biopython, published on 18 Dec 2025. Any signed-in user can exploit it over the network, with no action from the victim.\nExploitation: There is no known exploitation of CVE-2025-68463 in the wild and no public exploit code.\n\nAffected packages and fixed versions:\n- biopython (PyPI): affected all versions up to 1.86; no fix listed\n- biopython (PyPI): affected all versions up to 1.86; no fix listed\n- biopython (PyPI): affected all versions; fixed in 1.87\n\nTask:\n1. Search the dependency manifests and lockfiles (for example package.json, package-lock.json, requirements.txt, poetry.lock, uv.lock, pom.xml, build.gradle, go.mod, Cargo.lock, Gemfile.lock) and any Dockerfiles for the affected packages, including transitive dependencies.\n2. If an affected version is in use, upgrade it to the fixed version for its release line with the project's package manager, so the lockfile is regenerated. Prefer the smallest upgrade that fixes it.\n3. If there is no fix, or the upgrade would break the build, do not guess: explain the risk and the safest workaround instead.\n4. Run the tests and summarise what changed and why.\n5. If nothing in the project is affected, say so and change nothing.\n\nReference: https://insights.sbomify.com/CVE-2025-68463/ (Markdown: https://insights.sbomify.com/CVE-2025-68463/index.md)","id":"CVE-2025-68463","markdown":"https://insights.sbomify.com/CVE-2025-68463/index.md","name":"CVE-2025-68463","record":{"aliases":["DEBIAN-CVE-2025-68463","GHSA-x3vf-39hj-gxr4","PYSEC-2026-1221","UBUNTU-CVE-2025-68463","openSUSE-SU-2026:10537-1","openSUSE-SU-2026:21169-1"],"analysis":{"component_type":"library","fix_type":"upgrade","impacts":["data_read","denial_of_service"],"network_reachable":"yes","non_default_config":false,"product_category":"Python bioinformatics library","requires_auth":"low_privilege","summary":"An attacker can exploit an XML External Entity vulnerability in Bio.Entrez to read sensitive files or cause denial of service.","user_interaction":"not_required","vuln_class":"xxe"},"analysis_generated_by":"qwen3.8-flash-next","assigner":"mitre","cpe":[],"cvss":{"score":4.9,"severity":"medium","source":"cna","vector":"CVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:C/C:L/I:N/A:L","version":"3.1"},"cwes":[{"id":"CWE-611","name":"Improper Restriction of XML External Entity Reference"}],"description":"Bio.Entrez in Biopython through 186 allows doctype XXE.","ecosystems":["PyPI","openSUSE:Leap 16.0","openSUSE:Tumbleweed"],"exploits":{"exploitdb":0,"first_seen":null,"github_poc":0,"max_poc_stars":null,"metasploit":0,"nuclei":0,"refs":[],"tier":"none_known"},"has_fix":true,"headline":"Biopython is vulnerable to doctype XML external entity (XXE) injection through Bio.Entrez","id":"CVE-2025-68463","indexable":true,"kev":null,"kind":"cve","links":{"ecosystem":"PyPI","product":null,"products":[],"type":"xxe","year":"2025"},"n_packages":5,"n_references":4,"next":{"headline":"Dark Reader gives users the ability to request style sheets from local web servers","id":"CVE-2025-68467"},"packages":[{"ecosystem":"PyPI","fixed":[],"introduced":["0"],"last_affected":["1.86"],"package":"biopython","purl":null,"source":"GHSA-x3vf-39hj-gxr4"},{"ecosystem":"PyPI","fixed":[],"introduced":["0"],"last_affected":["1.86"],"package":"biopython","purl":"pkg:pypi/biopython","source":"GHSA-x3vf-39hj-gxr4"},{"ecosystem":"PyPI","fixed":["1.87"],"introduced":["0"],"last_affected":[],"package":"biopython","purl":"pkg:pypi/biopython","source":"PYSEC-2026-1221"},{"ecosystem":"openSUSE:Leap 16.0","fixed":["1.85-bp160.2.1"],"introduced":["0"],"last_affected":[],"package":"python-biopython","purl":"pkg:rpm/opensuse/python-biopython\u0026distro=openSUSE%20Leap%2016.0","source":"openSUSE-SU-2026:21169-1"},{"ecosystem":"openSUSE:Tumbleweed","fixed":["1.87-1.1"],"introduced":["0"],"last_affected":[],"package":"python-biopython","purl":"pkg:rpm/opensuse/python-biopython\u0026distro=openSUSE%20Tumbleweed","source":"openSUSE-SU-2026:10537-1"}],"prev":{"headline":"Information disclosure in FreedomBox","id":"CVE-2025-68462"},"products":["Biopython"],"published":"2025-12-18","related":[],"sources":[{"class":"attribution","licence":"CVE Terms of Use (MITRE)","name":"CVE List","prefix":"CVE"},{"class":"attribution","licence":"CC BY 4.0","name":"GitHub Advisory Database","prefix":"GHSA"},{"class":"attribution","licence":"CC BY 4.0","name":"PyPA Advisory Database","prefix":"PYSEC"},{"class":"attribution","licence":"CC BY 4.0","name":"SUSE","prefix":"openSUSE"},{"class":"attribution","licence":"CWE Terms of Use","name":"CWE (MITRE)"},{"class":"attribution","licence":"FIRST CVSS licence","name":"CVSS (FIRST)"}],"ssvc":{"automatable":"no","exploitation":"none","technical_impact":"partial"},"state":"PUBLISHED","updated":"2026-05-08","vendors":["Biopython"]},"summary":"An attacker can exploit an XML External Entity vulnerability in Bio.Entrez to read sensitive files or cause denial of service.","url":"https://insights.sbomify.com/CVE-2025-68463/"}