CVE-2026-109361 MONAI 1.2.0 before 1.6.1 Insecure Deserialization RCE via nnUNetV2Runner postprocessing_file Path

High 7.0 Published Updated

Attackers can execute arbitrary code by modifying inference configuration to point to a malicious pickle file in MONAI.

Exploited in the wild
Not known
Login needed
Any signed-in user
Attackable
Local or same network only
Victim action needed
A user has to click or open something
Fix
None listed

What is CVE-2026-109361?

CVE-2026-109361 is a high-severity unsafe deserialization vulnerability in Project-MONAI MONAI, published on 12 Oct 2026. It can only be exploited from the same machine or local network, and only if a user opens a file or follows a link.

Official description

MONAI 1.2.0 before 1.6.1 contains an insecure deserialization vulnerability in nnUNetV2Runner that unpickles the postprocessing_file path read from inference_information.json without confining it to the results directory. Attackers who can modify inference_information.json can point it at a malicious pickle elsewhere on the filesystem to execute code when predict_ensemble_postprocessing runs.

Weakness: CWE-502

Which versions are affected by CVE-2026-109361?

How do I fix CVE-2026-109361?

No fix has been published for CVE-2026-109361 yet. Limit exposure of the affected software until one is available.

Upgrade, and only deserialise data from trusted sources or with an allow-list of types. More about Unsafe deserialization.

Is CVE-2026-109361 being exploited?

There is no known exploitation of CVE-2026-109361 in the wild and no public exploit code.

Sources

Also known as GHSA-7hmf-j253-4p2j, GHSA-8f32-8649-rv87.

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