# CVE-2026-17583: Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check

> Attackers can tamper with DNA output files to alter test results, impacting the integrity of genetic analysis data.

- **Severity:** High 8.3 (`CVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:N/VC:N/VI:H/VA:H/SC:N/SI:H/SA:N`)
- **Exploited in the wild:** Not known
- **Login needed:** Not needed
- **Attackable:** Local or same network only
- **Victim action needed:** Not needed
- **Fix available:** No
- **Published:** 5 Aug 2026
- **Updated:** 6 Aug 2026
- **Also known as:** GHSA-5p87-q7f6-jf7x, UBUNTU-CVE-2026-17583

## What is CVE-2026-17583?

CVE-2026-17583 is a high-severity vulnerability in Thermo Fisher ABI PRISM 310 Data Collection Software, published on 5 Aug 2026. It can only be exploited from the same machine or local network, with no action from the victim.

### Official description

The affected

Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

Weakness: CWE-353 (Missing Support for Integrity Check)

## Which versions are affected by CVE-2026-17583?

It affects 8 products.


Products: Thermofisher Abi Prism 3100\/3100-Avant Data Collection Software, Thermofisher Abi Prism 310 Data Collection Software, Thermofisher Applied Biosystems 3130 Series Data Collection Software, Thermofisher Applied Biosystems 3500\/3500xl Series Data Collection Software, Thermofisher Applied Biosystems 3730\/3730xl Series Data Collection Software, Thermofisher Applied Biosystems Seqstudio Flex Series Instrument Software, Thermofisher Applied Biosystems Seqstudio Genetic Analyzer Data Collection Software, Thermofisher Genemapper Id-X.

## How do I fix CVE-2026-17583?

No fix has been published for CVE-2026-17583 yet. Limit exposure of the affected software until one is available.

## Is CVE-2026-17583 being exploited?

There is no known exploitation of CVE-2026-17583 in the wild and no public exploit code.

Public exploit code:

- CVE-2026-17583 - Draft (github_poc): https://github.com/HORKimhab/CVE-2026-17583

## Fix prompt for AI coding agents

```text
Check this codebase for CVE-2026-17583 and fix it if it is affected.

What it is: CVE-2026-17583 is a high-severity vulnerability in Thermo Fisher ABI PRISM 310 Data Collection Software, published on 5 Aug 2026. It can only be exploited from the same machine or local network, with no action from the victim.
Exploitation: There is no known exploitation of CVE-2026-17583 in the wild and no public exploit code.

Affected product: Thermo Fisher ABI PRISM 310 Data Collection Software. No package-level version data is available, so check the vendor advisory linked from the reference page.

Task:
1. Search the dependency manifests and lockfiles (for example package.json, package-lock.json, requirements.txt, poetry.lock, uv.lock, pom.xml, build.gradle, go.mod, Cargo.lock, Gemfile.lock) and any Dockerfiles for the affected packages, including transitive dependencies.
2. If an affected version is in use, upgrade it to the fixed version for its release line with the project's package manager, so the lockfile is regenerated. Prefer the smallest upgrade that fixes it.
3. If there is no fix, or the upgrade would break the build, do not guess: explain the risk and the safest workaround instead.
4. Run the tests and summarise what changed and why.
5. If nothing in the project is affected, say so and change nothing.

Reference: https://insights.sbomify.com/CVE-2026-17583/ (Markdown: https://insights.sbomify.com/CVE-2026-17583/index.md)
```

## Sources

- CVE record: https://www.cve.org/CVERecord?id=CVE-2026-17583
- NVD: https://nvd.nist.gov/vuln/detail/CVE-2026-17583
- OSV: https://osv.dev/vulnerability/CVE-2026-17583

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From sbomify Insights: https://insights.sbomify.com/CVE-2026-17583/
Summaries are generated and may contain mistakes; the official description above is the record.